THYROID SUPPORT+

COMPREHENSIVE HORMONE SUPPORT*

OVERVIEW

Discover the power of Thyroid Support, a cutting-edge nutritional supplement meticulously formulated to promote optimal thyroid function and support overall thyroid health. Thyroid Support is a synergistic blend of selenium, iodine, vitamin K2, guggulsterone, diiodo-L-thyronine (T2), hydroxytyrosol acetate, and theobromine. This science-backed supplement addresses the entire hypothalamus-pituitary-thyroid axis, supports energy production, metabolic rate, mitochondrial function, and promotes overall thyroid metabolism. Thyroid Support is key to unlocking the full potential of thyroid functionality and metabolism to achieve a balanced, energized, and vibrant life.

INGREDIENTS

Selenium as L-Selenomethionine
Selenium, an essential trace mineral, is vital in thyroid hormone synthesis and metabolism. Itacts as a cofactor for enzymes involved in the conversion of thyroxine (T4) to its active form,triiodothyronine (T3).1 Selenium also exhibits antioxidant properties, shielding the thyroid gland from oxidative stress.2
Selenium works specifically on the activity of selenoproteins, particularly glutathioneperoxidases, which help neutralize reactive oxygen species (ROS) and maintain optimal thyroidfunction.3 It also contributes to regulating thyroid hormone levels by modulating the expression of genes involved in hormone synthesis.4
Selenium supplementation assists thyroid function by supporting the healthy production ofthyrotropin (TSH) levels and thyroxine (T4) to triiodothyronine (T3) conversion.5 These findingsunderscore the importance of selenium in supporting thyroid health.

Iodine from Potassium Iodide
Iodine is an essential mineral required for the synthesis of thyroid hormones. It is a keycomponent of thyroxine (T4) and triiodothyronine (T3), which regulate metabolism, growth, anddevelopment.6 Iodine is actively transported into thyroid follicular cells, combining with theamino acid tyrosine to form T4 and T3.7
These hormones are then released into circulation and affect various target tissues. Iodinedeficiency is a well-known cause of thyroid disorders, and supplementation with iodine has beenshown to be helpful in aiding overall thyroid function.8

Vitamin K2 as Menaquinone-7
Vitamin K2, specifically Menaquinone-7 (MK-7), is a remarkable nutrient that supports optimalthyroid function and overall health. MK-7 exhibits unique properties that contribute to thyroidmetabolism. It is an essential cofactor for activating vitamin K-dependent proteins involved incalcium metabolism and regulation.9 By regulating calcium homeostasis, MK-7 ensures properthyroid gland function and hormone synthesis because of the key interplay between calcium andthe thyroid gland.
A study involving postmenopausal women demonstrated that vitamin K2 supplementationsupported healthy thyroid function markers and lipid profile parameters.10 These findings suggest the potential of MK-7 to support thyroid health and metabolic balance.

Guggulsterone E-Z
Guggulsterone, derived from the resin of the Commiphora mukul tree, has been traditionallyused in Ayurvedic medicine to support thyroid function and metabolism.11Guggulsterone has been shown to support the activity of enzymes involved in thyroid hormonemetabolism.12 It also exhibits antioxidant activity, further supporting thyroid health.A study investigating the effects of guggulsterone in an animal model demonstrated its ability topromote thermogenesis in brown adipose tissue, energy expenditure, and metabolic rate.13

Hydroxytyrosol Acetate

Hydroxytyrosol, a phenolic compound found in olive oil, exhibits antioxidant properties, makingit beneficial for thyroid health and supporting its proper function.14,15,16 Research has indicated the antioxidant and DNA-supportive activities of hydroxytyrosol acetate, emphasizing its potential benefits in shielding the thyroid from excessive oxidative stress.17

Theobromine

Theobromine, a natural compound found in cocoa beans, offers several potential methods ofsupport for thyroid health and metabolism.18 While the data around theobromine is predominately centered around its antioxidant capacity, it has a direct influence, albeit to a lesser extent than caffeine, on brain function. This is key to people struggling with their thyroid function as ‘brain fog’ or ‘brain fatigue’ are common complaints in these people. However, as it relates directly to the thyroid function itself, theobromine has been shown to interact with thyroid hormone receptors, influencing their activity and supporting thyroid function.19

REFERENCES

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20. De Lange, P ., Senese, R., Cioffi, F., Moreno, M., Lombardi, A., Silvestri, E., ... & Lanni, A. (2011). Endocrinology, 152(2), 605-616.

21. Lombardi, A., de Lange, P ., Silvestri, E., Busiello, R. A., Lanni, A., & Goglia, F. (2015). Moreno, M. Thyroid, 25(10), 1192-1201.

22. Senese, R., Cioffi, F., de Lange, P ., Goglia, F., & Lanni, A. (2013). Journal of Endocrinology, 218(1), R1-R12.